Learning Cannabinoids:

What Are Cannabinoids:

Learn about the different cannabinoids and how they can help you improve your health

A cannabinoid is one of the broad classes of chemical substances that activate cannabinoid receptors in the cells altering neurotransmitter release in the brain. The substances that trigger these protein receptors are Endocannabinoid, Phytocannabinoid, and synthetic cannabinoids. The most widely known cannabinoid is the Phytocannabinoid tetrahydrocannabinol (THC); it is one of the psychoactive substances in cannabis. Cannabidiol (CBD) is a different known component of the plant. There are at least 101 different cannabinoids derived from cannabis and hemp, each exhibiting different effects when consumed.

 

What are Cannabinoids used for?

A cannabinoid is sometimes used for medical reasons; they are used in the treatment of nausea arising from chemotherapy, spasticity, and neuropathic pain. The side effects of cannabinoids range from feeling high to feeling sedated and relaxed. Research on cannabinoids has shown some promising effects on anxiety reduction, reduced inflammation, and slowing the growth of tumors. The effect of a Cannabinoid is the result of its interaction with special receptors in the cell surface known as CB1 or CB2 Receptors.

TYPES OF CANNABINOID RECEPTORS:

There are generally two types of receptors present in the body known as CB1 and CB2. You should know that the human brain has more cannabinoid receptors than any G protein-coupled receptor (GPCR) in the world.

 

CANNABINOID RECEPTOR TYPE 1

CB1 is primarily found in the brain. It is found in the basement ganglia and in the limbic system. This also includes the hippocampus and the striatum. CB1 receptors can also be found in the cerebellum, and the cannabinoid receptors are present in the male and female reproductive system. The medulla oblongata is another area where the receptor is found; this part of the brain is responsible for the respiratory and cardiovascular function of the body. CB1 receptors can also be found in parts of the eye responsible for vision. .

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CANNABINOID RECEPTOR TYPE 2

CB2 receptors are dominant in the immune system, or the immune-derived cells with a majority found in the spleen. Reports have shown that a small percentage of CB2 is present in the microglia of the human cerebellum. It is responsible for the anti-inflammatory and other therapeutic effects of cannabis that is seen in animals.

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